Ketoconazole is an anti-fungal medication used to treat susceptible infections from yeasts and other fungi. Ketoconazole may also be used with other medications to treat other disorders such as Canine Cushing's Disease. 

Dogs and Cats

Ketoconazole is used to treat internal and external fungal infections.

ketoconazole

Side effects may include loss of appetite, vomiting and diarrhea. If symptoms of diarrhea, vomiting and lack of appetite persist, contact your veterinarian. Lightening of the hair coat may occur.

Other side effects may occur. If you notice anything unusual, contact your veterinarian.

Ketoconazole should be given orally as directed by your veterinarian.

This medication does not have an FDA approved indication for use in animals, but it is a common and acceptable practice for veterinarians to prescribe this human medication for use in animals.

Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. The following lists examples of medicines that can potentially interact with ketoconazole: antacids, amitriptyline, clomipramine, benzodiazepines, buspirone, calcium channel blockers, corticosteroids, digoxin, ivermectin, sucralfate, cimetidine, ranitidine, propantheline, mitotane, warfarin, phenytoin, methylprednisolone, cisapride, theophylline, rifampin, isoniazid, acyclovir, and cyclosporine. The following medications should not be given with ketoconazole: astemizole, cisapride or terfenadine. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.