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IB# 107074
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Comfortis is the first FDA-approved, chewable, beef-flavored tablet that kills fleas and prevents flea infestations on dogs and cats for a full month. Each tablet contains spinosad.


Dogs and Cats


Comfortis is used to treat and prevent flea infestations.

  • Beef-flavored, palatable, chewable tablet 
  • Easy to give with no mess 
  • Starts to kill fleas in 30 minutes
  • Lasts a full month 
  • Kills fleas before they can lay eggs 
  • Approved by the FDA
  • Demonstrated safe for dogs and cats 14 weeks and older

Along with fast-acting, month-long flea protection, Comfortis offers these additional benefits:

  • With Comfortis you can play with your pet immediately after treatment. No need to isolate pets. Just treat and play.
  • Comfortis won't stain carpeting, upholstery or clothing.
  • Comfortis can't be rubbed or shaken off.
Active Ingredients


Side Effects

Side effects may include nausea, vomiting, diarrhea, loss of appetite, and decreased activity. Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, a component of Comfortis. If you notice anything unusual, contact your veterinarian.


Comfortis should be given orally as directed by your veterinarian. If vomiting occurs within an hour of administration, redose with another full dose.


The safety of Comfortis has not been established in breeding, pregnant, or lactating animals. Use with caution in dogs with pre-existing epilepsy.

Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.

IB# 107074
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