Product Information

Ondansetron is an antiemetic indicated for the prevention and treatment of severe vomiting in dogs and cats. 

For

Dogs & Cats

Generic Name

Ondansetron

Brand Names

Zofran

Drug Class

5-HT3 Receptor Antagonist

Product Description & Form

Indicates current product being dispensed

Ondansetron 4 mg Tablets 30 ct: 6 mm, white (white to off-white), oval tablet, not scored, imprinted with F;91.  (NDC 65862-0187-30)

Ondansetron 8 mg Tablets 30 ct: 8 mm, yellow, oval tablet, not scored, imprinted with F;92.  (NDC 65862-0188-30)

Benefits

• Used to prevent and treat severe vomiting in dogs and cats
• Can be effective in treating chemotherapy-associated vomiting

Active Ingredients

ondansetron

Inactive Ingredients

Indicates current product being dispensed

Ondansetron 4 mg Tablets 30 ct: anhydrous lactose, microcrystalline cellulose, corn starch, magnesium stearate, triacetin, titanium dioxide, hypromellose 2910. (NDC 65862-0187-30)

Ondansetron 8 mg Tablets 30 ct: anhydrous lactose, microcrystalline cellulose, corn starch, magnesium stearate, triacetin, titanium dioxide, hypromellose 2910, ferric oxide yellow. (NDC 65862-0188-30)

Usage:

Ondansetron should be given orally as directed by your veterinarian.

Missed Doses

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.

Side Effects

Side effects are uncommon. Rare side effects may include constipation, sleepiness, or head shaking. Rare but serious side effects include abnormal heart rhythms and low blood pressure, which may cause fainting/collapse or severe lethargy. These symptoms may go away during treatment. If these symptoms continue, contact your veterinarian. 

Other side effects may occur. If you notice anything unusual, contact your veterinarian.

Drug & Food Interactions

Make sure to tell your veterinarian what other medication you are giving your pet. The following medications should be used with caution when given with ondansetron: apomorphine, azole antifungals, cisplatin, cyclophosphamide, certain heart medications, metformin, MAO inhibitors, serotonergic drugs, or tramadol.

Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely.

Cautions

The safety of Ondansetron has not been established in breeding, pregnant, or lactating dogs. Ondansetron should not be used in pets that are allergic to it. It should be used cautiously in pets with gastrointestinal blockage, certain abnormal heart rhythms, or liver disease. 

Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.

Adverse Reactions

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource customer service at 877-738-4443.

Storage

Store at 68°F to 77°F in controlled room temperature. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.

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